The response of the pixel detector TimePix to ions in the 4–110 MeV kinetic energy range and A=1–136 mass range has been studied using the fission–fragment separator Lohengrin of the Institute Laue Langevin in Grenoble. For heavy charged particles TimePix can measure their (i) location and spatial distribution, (ii) kinetic energy, and (iii) time of arrival. Pixel signal distortion and saturation arise when large charge is locally deposited and can be minimized by suitable detector settings of baseline and threshold together with suitable low bias voltage.