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IEAP - Institute of Experimental and Applied Physics CTU - Czech Technical University in Prague
CTU - Czech Technical University in Prague
Publication  > Articles in Impacted Journals  > 'Multimodal imaging with hybrid semiconductor detectors Timepix for an experimental MRI-SPECT system'
Multimodal imaging with hybrid semiconductor detectors Timepix for an experimental MRI-SPECT system

Author
Zajíček Jiří, Ing. IEAP
Jakůbek Jan, Ing. Ph.D. IEAP
Burian Martin, Mgr. IKEM
Vobecký Miloslav, Ing. CSc. IEAP
Fauler A FMF University of Freiburg
Fiederle M FMF University of Freiburg
Zwerger Andreas, Ing. Freiburger Materialforschungszentrum, Albert-Ludwigs-Universität Freiburg, Germany

Year
2013

Scientific journal
Journal of Instrumentation

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Abstract
An increasing number of clinical applications are being based on multimodal imaging systems (MIS), including anatomical (CT, MRI) and functional (PET, SPECT) techniques to provide complex information in a single image. CT with one of the scintigraphic methods (PET or SPECT) is nowadays a combination of choice for clinical practice and it is mostly used in cardiography and tumour diagnostics. Combination with MRI is also being implemented as no radiation dose is imparted to the patient and it is possible to gain higher structural resolution of soft tissues (brain imaging). A major disadvantage of such systems is inability to operate scintillators with photomultipliers (used for detection of g rays) in presence of high magnetic fields. In this work we present the application of the semiconductor pixel detector for SPECT method in combination with MR imaging. We propose a novel approach based on MRI compatible setup with CdTe pixel sensor Timepix and non-conductive collimator. Measurements were performed on high proton-density (PD) phantom (1H) with an embedded radioisotopic source inside the shielded RF coil by MRI animal scanner (4.7 T). Our results pave the way for a combined MRI-SPECT system. The project was performed in the framework of the Medipix Collaboration. KEYWORDS: Gamma detectors (scintillators, CZT, HPG, HgI etc); Gamma camera, SPECT, PET PET/CT, coronary CT angiography (CTA); Pixelated detectors and associated VLSI electronics; Hybrid detectors
Grants


Cite article as:
J. Zajíček, J. Jakůbek, M. Burian, M. Vobecký, A. Fauler, M. Fiederle, A. Zwerger, "Multimodal imaging with hybrid semiconductor detectors Timepix for an experimental MRI-SPECT system", Journal of Instrumentation (2013)

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