IEAP - Institute of Experimental and Applied Physics

Partial tasks > Biological Imaging with X-rays

Biological Imaging with X-rays

Biological Imaging with X-rays and Medipix detectors. The single quantum counting pixel device Medipix2 serves as imaging area. Detectors Medipix2 do not suffer from so called dark current (noise) and work in non-limited dynamic range. These features of detectors confer high quality and high contrast of final images.The radiographic imaging with detectors Medipix2 represents non-invasive and non-destructive method of investigation.

Responsible person

Dammer Jiří

IEAP

Co-workers

Jakůbek Jan	IEAP
Vavřík Daniel	IEAP
Krejčí František	IEAP

Grants:

Number	Name	Agency
LC06041	Research center "Fabrication, modification and characterization of materials by energetic radiation"	MŠMT
MSM 6840770040	Research Program 40: Usage of radionuclides and ionizing radiation.	MŠMT

Articles in Impacted Journals
(14)

Articles in Conference Proceedings
(16)

Thesis
(1)

Other publications
(2)

All
(34)

Table format

J. Dudák, J. Žemlička, F. Krejčí, J. Karch, M. Patzelt, P. Zach, V. Sykora, . , "Evaluation of sample holders designed for long-lasting X-ray micro-tomographic scans of ex-vivo soft tissue samples", Journal of Instrumentation (2016)

O. Jiroušek, D. Kytýř, T. Doktor, F. Krejčí, "Displacement tracking in single human trabecula with metal-plated micro-spheres using X-ray radiography imaging", Journal of Instrumentation 8 C02041 (2013)

V. Sýkora, J. Žemlička, F. Krejčí, J. Jakůbek, "X-ray micro-radiography and microscopy of seeds", Science 339 (6119), 511 (2013)

F. Krejčí, M. Kroupa, J. Jakůbek, P. Brůža, D. Pánek, "Detection of Soft X-rays with the Pixel Detector Timepix operated as a highly sensitive Dark-Current free CCD-like Camera ", 2011 IEEE Nuclear Science Symposium Conference Record, NP5.S-166, 1708 - 1712 (2012)

J. Dammer, F. Weyda, J. Benes, V. Sopko, J. Jakůbek, V. Vondracek, "Microradiography of biological samples with Timepix", JINST 6 C11005 doi:10.1088/1748-0221/6/11/C11005 (2011)

F. Krejčí, J. Jakůbek, M. Kroupa, "Single grating method for low dose 1-D and 2-D phase contrast X-ray imaging", Journal of Instrumentation 6 C01073 (2011)

P. Soukup, J. Jakůbek, I. Jandejsek, J. Žemlička, "X-ray color imaging with 3D sensitive voxel detector", JINST 6 C12014 doi:10.1088/1748-0221/6/12/C12014 (2011)

P. Vrba, M. Vrbová, P. Brůža, D. Pánek, F. Krejčí, M. Kroupa, J. Jakůbek, "XUV radiation from gaseous nitrogen and argon target laser plasmas ", Journal of Physics: Conference Series (2011)

F. Krejčí, J. Jakůbek, M. Kroupa, " Hard x-ray phase contrast imaging using single absorption grating and hybrid semiconductor pixel detector", Rev. Sci. Instrum. 81, 113702 (2010)

F. Krejčí, J. Jakůbek, M. Kroupa, "Low dose X-ray phase contrast imaging sensitive to phase effects in 2-D ", IEEE NSS/MIC/RTSD Knoxville Conf. Record M09-166, doi: 10.1109/NSSMIC.2010.5874172

F. Krejčí, J. Jakůbek, M. Kroupa, "New approach in phase contrast X-ray imaging using coded aperture", 11th ICATPP Conference, Villa Olmo - Como (Italy), 5-9 October 2009, ISBN 10 981-4307-51-2, pp. 59 – 63 (2010)

J. Dammer, P. Frallicciardi, J. Jakůbek, M. Jakůbek, S. Pospíšil, E. Prenerová, D. Vavřík, L. Volter, F. Weyda, R. Zemek, "Real-time in-vivo µ-imaging with Medipix2", NIM A, Vol. 607, Issue 1, p. 205-207 (2009)

J. Jakůbek, J. Dammer, T. Holý, M. Platkevič, J. Uher, Z. Vykydal, "Digital radiography with pixel detectors of Medipix family", Československý Časopis pro Fyziku, 1/2008, 25-36

J. Jakůbek, "Energy sensitive micro-radiography and micro-tomography of biological samples allowing tissue type recognition with semiconductor pixel detectors of Medipix family", EPSM ABEC 2008, Conference handbook, ISBN 0 8582 5872 2, (p. 265)

J. Dammer, F. Weyda, "Microradiography of biologic objects using pixel detectors", Živa 6/2008, p 286-288

J. Dammer, J. Jakůbek, D. Vavřík, "Microradiography of biological samples", Československý Časopis pro Fyziku, 1/2008, 50-52

J. Jakůbek, A. Cejnarová, T. Holý, S. Pospíšil, J. Uher, Z. Vykydal, "Pixel Detectors for Imaging with Heavy Charged Particles", Nucl. Instr. and Meth. A, Volume: 591, Issue:1, Pages: 155-158, doi: 10.1016/j.nima.2008.03.091

P. Skrabal, "Processes in biological microimaging (Supervisor: J. Jakubek) in progress", Master Thesis, Charles U. Prague (2008)

P. Frallicciardi, J. Dammer, F. Weyda, J. Jakůbek, D. Vavřík, S. Pospíšil, "Real-Time X-Ray 2-D and 3-D Micro-Imaging of Living Animals with Medipix2 Single Photon Counting Detector", Conf. Proc. IEEE NSS/MIC 2008, M10-112

J. Dammer, J. Jakůbek, R. Hanus, F. Weyda, D. Vavřík, "Real-time in-vivo imaging of small organisms", ICATPP congf. proceedings, p. 640-644 (2008)

J. Jakůbek, J. Dammer, C. Granja, T. Holý, S. Pospíšil, J. Uher, "Compact system for high resolution X-ray transmission radiography, in-line phase enhanced imaging and micro CT of biological samples", IEEE NSS IEEE NSS Conf. Proc. 4179187 (2007) 1077-1080

J. Jakůbek, "Data processing and image reconstruction methods for pixel detectors", NIM A 576 (2007) 223-234, doi:10.1016/j.nima.2007.01.157

J. Dammer, T. Holý, J. Jakůbek, M. Jakůbek, S. Pospíšil, D. Vavřík, "In-vivo real-time X-ray µ-imaging", AIP Vol. 958 (2007), pp 139

D. Vavřík, T. Holý, J. Jakůbek, M. Jakůbek, "Microadiographic Measurement of Moving Material Structures", Proceedings of International Symposium on Technology for Next Generation Vehicle & Machine (2007)

J. Jakůbek, A. Cejnarová, J. Dammer, T. Holý, M. Platkevič, S. Pospíšil, D. Vavřík, Z. Vykydal, "Microradiography with Semiconductor Pixel Detectors", Amer. Inst. of Physics (AIP) Conf. Proc., Volume: 958, Pages: 131-135, doi: 10.1063/1.2825764 (2007)

J. Jakůbek, C. Granja, J. Dammer, R. Tykva, R. Hanus, J. Uher, Z. Vykydal, "Phase contrast enhanced high resolution X-ray imaging and tomography of soft tissue", Nucl. Instr. and Meth. A, Volume: 571, Issue: 1-2, Pages: 69-72, doi: 10.1016/j.nima.2006.10.031 (2007)

D. Vavřík, J. Dammer, T. Holý, J. Jakůbek, M. Jakůbek, I. Jandejsek, "Radiography of Chaotically Moving Objects", AIP Vol. 958 (2007) 139-142

R. Hanus, J. Dammer, T. Holý, J. Jakůbek, S. Pospíšil, R. Tykva, "Small-scale in vivo imaging of soft tissues by radioscopy using single X-ray photon counting", Journal of Microscopy 226 (2007) 191–194

D. Vavřík, T. Holý, J. Jakůbek, S. Pospíšil, Z. Vykydal, J. Dammer, "Direct thickness calibration: way to radiographic study of soft tissues", 9th ICATPP 2005 Conf. Proc., Pages: 773-778, doi: 10.1142/9789812773678_0122 (2006)

J. Jakůbek, J. Dammer, T. Holý, S. Pospíšil, J. Uher, "High Resolution Soft Tissue Tomographic Imaging using Single X-ray Photon Counting Pixel Device Medipix2", Conf.: New Technics in Lab Animal Science (2006)

R. Tykva, R. Hanus, J. Jakůbek, Z. Wimmer, V. Vlasáková, "Normalized model system for the study of termite management", XVIII World Congress IMEKO (2006)

C. Granja, J. Jakůbek, V. Linhart, M. Cevallos, J. Krug, "Dental Implant Imaging with Pixel Detectors", IEEE NSS Conference Record (2004) 3872-3876

D. Vavřík, J. Jakůbek, S. Pospíšil, J. Visschers, "Non-destructive observation of damage processes by X-ray dynamic defectoscopy", International Conference on the Mechanical Behaviour of Materials, Conf. Proc. (2003)