Beam Quality Assurance and Online Dose Verification in Hadrontherapy

Mohammad Varasteh Anvar, PhD

CERN - TERA foundation, Geneva, Switzerland


The importance of research and development in Charged Particle Therapy (CPT aka Hadrontherapy) is being proven by the rapid growth in the number of hadrontherapy facilities worldwide. The well-defined range of particle beams, enabling higher local control than conventional radiation therapy, makes hadrontherapy attractive for treating cancerous patients.

The quality assurance (QA) procedures in particle therapy centers with active beam scanning are based on single or arrays of ionization chambers and films, which are certainly precise but suffer from lengthy procedures. Developing an accurate and fast approach for QA checks of proton and carbon ion beams using the 2D MatriXX detector at the Italian Hadrontherapy Center is the first topic that will be discussed in this talk. This work verifies that the 2D MatriXX detector has enough sensitivity to replace films in three main objectives: beam positionmeasurement, beam width determination, and field dose uniformity andflatness. MatriXX device, engineered and commercialized by IBA (Be), isa pixel segmented ionization chamber array for real-time QA of conventional beams.

Although the CPT, delivered using scanned pencil beams, shows the potential to produce better dose conformity than conventional radiotherapy, the dose distributions are more sensitive to anatomicalchanges and patient motion. Therefore, the introduction of engines to monitor the dose as it is being delivered is highly desirable in order to enhance the development of adaptive treatment techniques in hadrontherapy. In the second part of the presentation, the INFN project called RIDOS (RealTime Ion Dose Planning and Delivery System) will be discussed. A tool for fast dose distributions analysis, which integrates a Fast Forward Planning, a Fast Image Deformation algorithm, a fast computation of Gamma-Index and Dose-Volume Histogram. To take into account the patient movements, registration methods are used totransform the 4DCT volumes at different respiratory phases to each other. The tool is being interfaced with the Dose Delivery System and the Optical Tracking System of a synchrotron-based facility to investigate the feasibility of quantifying the effects of organ movements on dose distributions during treatment.

Seminar takes place on Tuesday, April 11th 2017 at 2:00 PM
in the IEAP meeting room, Praha 2 ‐ Albertov, Horská 3a/22.

Dr. André Sopczak
seminar organizer
doc. Ing. Ivan Štekl, CSc.
Dr. André Sopczak
IEEE CS - NPSS chair

IEEE Czechoslovakia section

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